BMS 270/BMI 219 Features and Mechanisms of Neurodegenerative Diseases: Focus on data derived from studies in humans (2021)

Module: 2
Sponsoring Program: BMS/BMI
Administrator: Priscilla Pereira

STUDY LIST INFORMATION
Course Number: BMS 270/BMI 219
Course Name: Special Topics
Units: 3
Grading Option: S/U
Course Director: Lea Grinberg

MORE COURSE INFORMATION
Other faculty: TBD
Dates: April 19 - May 7
Schedule: Mon, Thurs and Fri, 9:00a-12:00p
Maximum Class Size: 12

Course Description: Neurodegenerative diseases are among the most common causes of disability and death worldwide. Despite years of research and clinical trial investiments, disease-modifying treatment for any neurodegenerative disease is elusive. Lack of translation between experimental models and disease features in humans in considered an important contributor to failures in clinical trials.   This course aims to provide insights on the natural history of neurodegenerative disease in humans including common features among neurodegenerative diseases, mechanisms of selective vulnerability and disease spread, role of neuroinflammation and clinicopathological correlations.  The attendees will also discuss about pros and cons of human-based and animal model-based approaches to decipher mechanisms and develop treatment for neurodegenerative diseases and initiatives to close these gaps. This course is intended for those interested in acquiring a solid basis on different aspects of neurodegenerative diseases in humans and was designed for those with interest in pursuing studies in humans or in experimental models alike. Students will be engaged by short formal lectures, journal clubs and  workshops. We will also touch in advances in methodological technology in this field.