BMS 270 Tissue Immunology (2023)

Module: 1
Sponsoring Program: BMS
Administrator: Priscilla Perreira

STUDY LIST INFORMATION
Course Number: BMS 270
Course Name: Tissue Immunology
Units: 3
Grading Option: S/U
Course Director: Roberto Ricardo-Gonzalez

MORE COURSE INFORMATION
Co-director: Sagar Bapat
Other faculty: Ari Molofsky, Anna Molofsky, Rich Locksley, Peter Turnbaugh, Tiffany Scharschmidt
Dates: April 3 - 21
Campus: PH
Location: CS-1116 & 1117
Schedule: M/W/F 3:00 - 5:00 pm
Minimum Class Size: 4
Maximum Class Size: 12

The immune system is compartmentalized between secondary lymphoid organs and various unique tissue sites. In these unique organ-specific environments, tissue-resident immune cells crosstalk with parenchymal and stromal cells to orchestrate normal tissue development, remodeling, and response to infection. Although typically physiologic, these immune processes frequently go awry in a wide range of human diseases. Understanding the immune players that drive inflammatory diseases may provide opportunities to develop tissue-targeted therapies. In this mini-course, we will do a ‘deep-dive’ on tissue-resident immune cells and how they integrate into tissue physiology. Each session will be presented by a UCSF immunologist/tissue biologist and will focus on a unique organ. Topics include lung, brain, skin, intestine (x2 sessions), and adipose tissue. We also hope to have an outside guest lecturer that integrates tissue immunology at the organismal level. Sessions will include a brief didactic overview of the organ that will describe organ function, common organ-specific diseases, and the role of tissue-resident immune cells. Following this, the faculty instructor will lead a journal club, with students jointly presenting and discussing a recent and high-impact paper on tissue immunology of the organ. We anticipate student teams will present a topic of their choice in the final session. Students will be expected to attend and participate in all sessions, including reading each journal club paper, preparing journal club materials, and final team presentations as assigned. We look forward to exploring this rich area of active scientific investigation in this BMS Mini-Course!