BMS 270 Tissue Fibrosis: Pathophysiology and Therapeutic Opportunities (2022)

Module: 2
Sponsoring Program: BMS
Administrator: Priscilla Pereira

STUDY LIST INFORMATION
Course Number:
BMS 270
Course Name: Tissue Fibrosis: Pathophysiology and Therapeutic Opportunities
Units: 3
Grading Option: S/U
Course Director: Mallar Bhattacharya

MORE COURSE INFORMATION
Co-director:
Dean Sheppard, Claude LeSaux, and Jen Chen
Other faculty: Ryk Derynk, Paul Wolters, Tien Peng, Kevin Tharp , Hal Chapman, Scott Turner, Jen Chen 
Dates:
April 18-May 6
Campus: PH
Room: CS-1102&1103 except on 4/18 room CS-0101,  4/20 and 4/27 room CS-1107&1108
Schedule: MWF, 4:00-6:15
Maximum Class Size: 12


Course Description: Fibrosis is a dynamic process that can affect all major tissues in pathologic contexts, from liver cirrhosis to respiratory failure in COVID19 to cancer. It is a major cause of morbidity and mortality. The number of patients affected by fibrosis has increased every year, and there are no curative treatments.  Despite significant advances in our understanding of the pathobiology of fibrosis, the translation of this knowledge to treatments has been limited. The goal of this minicourse is to present the latest knowledge on fibrosis—the underlying pathobiology, and how research in both academic and industry is addressing this therapeutic challenge.

The course will be a discussion of a series of influential papers in conjunction with presentations from experts in the field from both academia and industry. The journal club portion will be for the graduate students who take the course, while the seminar will be open to the scientific community. At the end of this minicourse students will be able to

1- Identify common drivers of fibrosis across organs


2- Understand the role of epithelial, mesenchymal, and immune cells


3- Describe the development, progression, and resolution of fibrosis


4- Understand drug development for fibrosis