BMS 270 Immunology of neurologic diseases (2017)

Module: 3
Sponsoring Program: BMS
Administrator: Ned Molyneaux

Course Number:
Course Name: Immunology of neurologic diseases
Units: 3
Grading Option: S/U
Course Director:Scott Zamvil

Additional Course Director(s):
Room Number: MH-2105, except 5/16 and 5/31 in MH-1402
Campus: Mission Bay
Schedule: May 15-June 2, 2017; T, 2:00-4:15 PM, W, 1:00-3:15 PM, TH, 2:00-4:15 PM
Prerequisites: None
Maximum Class Size: 12

Course Description:This mini course will focus on recent advances in understanding cellular and humoral immune contributions to the pathogenesis of neuroinflammatory and neurodegenerative diseases, including multiple sclerosis, neuromyelitis optica, paraneoplastic conditions, autoimmune and infectious encephalitis, Alzheimer’s disease and Parkinson’s disease.  Articles chosen for discussion will explore the involvement of innate and adaptive immune responses, including the gut-brain axis, in the pathogenesis of these human diseases and in experimental models. The course will emphasize the application of modern technologies to studying these conditions, including deep sequencing (e.g., bulk transcriptomics, metagenomics immune repertoire sequencing and single cell genomics), advanced imaging (e.g., magnetic resonance imaging, nuclear medicine techniques and two-photon microscopy), and gene editing