BMS 270 Advances in understanding humoral immunity in humans (2016)

Module: 1
Sponsoring Program: BMS
Administrator: Demian Sainz

Course Number: BMS 270
Course Name: Advances in understanding humoral immunity in humans
Units: 3
Grading Option: S/U
Course Director: Jason Cyster

Additional Course Director(s): None
Room Number: TBA
Campus: Parnassus
Schedule: April 4-15, 2016;  M-F,  2:00 PM-4:00 PM
Prerequisites: None
Maximum Class Size: 12

Course Description: The convergence of advances in isolating single antigen-reactive B cells and in deep sequencing of immunoglobulin (Ig) genes has led to remarkable insights into the properties and dynamics of human antibody responses. Through a series of discussion papers, this minicourse will review the current technologies used for tracking human B cell responses while teaching about the advances that have been made in understanding human broadly neutralizing antibody responses against HIV-1 and influenza virus; the B cell response against malaria; and B cell responses occurring in autoimmune disease. The minicourse will provide an opportunity to reinforce your knowledge about antibodies, and about germinal center, plasma cell and memory B cell responses, and it will discuss findings that are guiding efforts to develop vaccines capable of inducing broadly neutralizing antibodies against viruses.