BMI 219 Computational Evolutionary Genomics (2016)

Module: 3
Sponsoring Program: BMI
Administrator: Julia Molla

Course Number: BMI 219
Course Name: Computational Evolutionary Genomics
Units: 3
Grading Option: S/U
Course Director: Ryan Hernandez

Additional Course Director(s):
Room Number: BH-212
Campus: Mission Bay
Schedule: May 9-27, 2016; M,W,F 10:30 AM-Noon
Prerequisites:  BMI206 or approval by course director
Maximum Class Size: Open
Course Description: We can now collect unprecedented amounts of genomic data using high throughput technologies.  In this course we will take an evolutionary approach toward understanding such patterns of genetic variation.   We will start with population genetics to develop an understanding of how the evolutionary forces of demography, recombination, and natural selection drive changes in the patterns of genetic variation that are introduced by random mutations.  We will then discuss comparative genomics to develop an understanding of long-term evolutionary processes.  Finally, we will consider the role of evolutionary processes in shaping patterns of human disease susceptibility.  Each week we will read papers from the literature and implement their statistical methods in R.  While programing in R will be required, guidance and assistance will be given to reduce the burden for students that are eager to learn.