Module: 2

Sponsoring Program: Tetrad
Administrator: Toni Hurley

STUDY LIST INFORMATION
Course Number: Biochem 210
Course Name: Classic Papers on the Cytoskeleton
Units: 3
Grading Option: S/U
Course Director: Dyche Mullins

MORE COURSE INFORMATION
Other faculty: TBA
Date: April 20 - May 8
Schedule: Mon, Wed, Fri 10:00a-12:00p
Maximum Class Size: 12
This Minicourse will be offered online. Instructions for ZOOM meetings will be sent by the course director.

Course Description: What is the secret of life? That's easy: macromolecular self-assembly. Who are the champions of self-assembly? The cytoskeletal proteins, or course. Across all three domains of life proteins related to actin, tubulin, and intermediate filaments assemble into polymers that move cargo, provide mechanical support, and establish order in the cytoplasm. In this course we will take a deep dive into the classic literature of the cytoskeleton, beginning with the earliest observations of the mitotic spindle and the discoveries of actin and myosin. We will read the seminal papers that created our current understanding of cytoplasmic organization and cellular architecture. Along the way, we will also discuss scientific writing; analyze the elements of a classic paper; and explore the deep connection between writing and discovery.